Copernicus’s De revolutionibus and Girolamo Fracastoro’s Homocentrica were both addressed to Pope Paul III. Their dedicatory letters represent a rhetorical exercise in advocating an astronomical reform and an attempt to obtain the papal favour. Following on from studies carried out by Westman and Barker & Goldstein, this paper deals with cultural, intellectual and scientific motives of both texts, and aims at underlining possible relations between them, such as that Copernicus knew of Fracastoro’s Homocentrica, and that at least part of the (...) rhetorical strategy laid out in De revolutionibus’s dedicatory letter can be read as a sophisticated response to Fracastoro’s arguments.Keywords: Copernicus; Fracastoro; Paul III; History of astronomy; Patronage. (shrink)

Based on research on the increasingly popular unconscious thought effect (UTE), it has been suggested that physicians might make better diagnostic decisions after a period of distraction than after an equivalent amount of time of conscious deliberation. However, published attempts to demonstrate the UTE in medical decision making have yielded inconsistent results. In the present study, we report the results of a meta-analysis of all the available evidence on the UTE in medical decisions made by expert and novice clinicians. The (...) meta-analysis failed to find a significant contribution of unconscious thought to the accuracy of medical decisions. This result cannot be easily attributed to any of the potential moderators of the UTE that have been discussed in the literature. Furthermore, a Bayes Factor analysis shows that most experimental conditions provide positive support for the null hypothesis, suggesting that these null results do not reflect a simple lack of statistical power. We suggest ways in which new studies could usefully provide further evidence on the UTE. Unless future research shows otherwise, the recommendation of using unconscious thought to improve medical decisions lacks empirical support. (shrink)

The coexistence of genetically modified (GM) crops and non-GM crops is a myth because the movement of transgenes beyond their intended destinations is a certainty, and this leads to genetic contamination of organic farms and other systems. It is unlikely that transgenes can be retracted once they have escaped, thus the damage to the purity of non-GM seeds is permanent. The dominant GM crops have the potential to reduce biodiversity further by increasing agricultural intensification. There are also potential risks to (...) biodiversity arising from gene flow and toxicity to nontarget organisms from herbicide-resistant (HT) and insect-resistant (Bt) crops. Unless whole regions are declared GM agriculture free, the development of distinct systems of agriculture (GM and non-GM) will be impossible as GM agriculture emerges at the expense of all other forms of production. (shrink)

Helisaeus Roeslin’s manuscript Speculum et harmonia mundi, Das ist Wellt Spiegel Erster Theil was conceived as part of a broader project comprising a Speculum ecclesiae as well as a Speculum naturae. This project was connected with a Chronology aiming to establish the precise date of the most important events in history as well as to advance some conjectures about the approaching eschatological future. This article presents some recent discoveries that shed new light on Roeslin’s chronological work after 1579, most importantly (...) the incontrovertible attribution to Roeslin of the anonymous manuscript De potestatibus orbis Christiani, et politicis et ecclesiasticis, Discursus. Here Roeslin presented his discovery of the numerical proportions governing the numbers of spiritual and temporal potestates in the three historical periods, affirming that these numbers were now nearly fullfilled, along with their ensuing eschatological implications. We show how Roeslin published this discovery in his Kurtz Bedencken against the calendar reform and again in 1612 in a short tract on the occasion of the coronation of Emperor Matthias I. The article focuses in particular on the appended broadsheet Tabella des Welt Spiegels, which displayed the completion and culmination of history, according to the astronomical revolutions of the planets as well as the numbers of temporal and spiritual governors. (shrink)

We re-examine Mersenne's critique of Giordano Bruno concerning the question of the extension of the universe and the plurality of worlds as well as that of universal animation. For this, it is necessary to distinguish, especially in the examination of the first question, the strictly cosmological problem from its metaphysical and theological foundation in which the relation between God and the universe is resolved. Mersenne's critique fundamentally concerns this second side of our problem, according to his conviction that Bruno repeats (...) the age-old errors of philosophical paganism and reaffirms an 'impiety' completely incompatible with Christian doctrine.------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------. (shrink)

Higher plants must undergo a major developmental switch, the transition to flowering, if they are to successfully complete their life cycle. In many plants, the crucial decision of when to begin to produce flowers is primarily controlled by environmental signals. The process of floral induction involves the integration of the activities of two types of genes: those that control flowering time as a response to the environment as well as an endogenous clock, and those that determine the floral identity of (...) the cells. The first direct link between these two classes of genes has now been demonstrated(1). Forced expression of CONSTANS, a flowering‐time gene, promotes flowering through the transcriptional activation of LEAFY, a flower‐meristem‐identity gene. (shrink)